Galician Research

January 21, 2014

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You have been created to give answers to diseases without cure at present. Detractors of the experiment come more a business of selling of these dogs that medical objectives. They share more than 269 disease genes with humans, to dnder researchers argue the use of dogs. Research is conducted by the National University of Seoul, where the first cloned dog in history. It is not the first case of animals created with fluorescent properties for medical purposes. A few years ago knew, for example, the existence of fluorescent pigs created with a view to stem cell therapy. This summer has given to learn about new research, this time with dogs. For what exactly? Researchers seek answers to curb diseases such as Parkinson’s and Alzheimer’s with this curious (and controversial) method. Detractors, a formula business of sale of these dogs, whose price reaches the 100,000 dollars by puppy in the market. A group of South Korean scientists has managed to clone dogs modified human genetically and fluorescent properties that could help cure diseases and imply a new advance in medical research. On the outside of the laboratory led by Professor Lee Byeong-chun in Seoul National University can be heard barking from unique cloned dogs of the world, a milestone in the animal replication only achieved between these walls. Among them is Snuppy, an Afghan Greyhound who in 2005 became the first cloned dog in history under the direction of the controversial researcher Hwang Woo-suk, who resigned to acknowledge that he had falsified data for research on stem cells from cloned human embryos. This laboratory of the University of veterinary medicine, which was the Centre of attention of the international scientific community in 2005, has now changed the focus of his research and focuses on the cloning of dogs, a line of work that proved valid and beyond all doubt. The latest achievement of the team of Professor Lee is the creation of a dog’s breed Beagle, born in 2009, which revealed fluorescent properties while taking an antibiotic that activates his light skin, acquired by genetic manipulation. The animal is called Tagon and under ultraviolet light and a special filter shows a unique in its kind: reflects a strong green light in addition to attracting the attention of the public, might be useful to study cures to diseases. Said Lee, equal to that Tagon is activated the gene that causes your skin fluorescent green color to give you an antibiotic, you can attempt to apply a procedure similar to ailments human, so taking a medicine inducing genetic functions are activated when desired, such as a switch. The same principle inspired the creation of Ruppy, another beagle, whose DNA synthesized a protein which makes their tissues are of a red color, which in turn becomes florescente under ultraviolet light. That Ruppy vermilion color serves to demonstrate that the genetic insertion has worked, as a placeholder, it details Lee in his Office, filled with plush dogs. The Professor argues that the selection of dogs as the object of study is due to that you share more than 269 disease genes with humans, so it can serve research model for ailments like Parkinson’s disease. However, these experiments are facing great difficulty posed by cloning a dog, much larger and expensive than the process required for a mouse or a sheep, as a pioneer Dolly. But in this laboratory have managed to find him at his work for years, recognized by publications such as Time Magazine and New York Times, a lucrative part; the sale of clones of dogs who died their distressed owners. $100,000 per puppy this business is done through the private company RNL Bio, which can charge more than $100,000 per puppy, price that does not dissuade people with large incomes worldwide. In addition, Lee and his team have successfully cloned species at risk such as the Korean Wolf or create a line of dogs with the best smell for customs or to detect tumors, a quality that only have certain hounds. A Spanish research Begona Roibas, a Spaniard who came to the Center in early 2010, works on the cloning of transgenic cows that produce a protein in its milk related to the immune system. This Galician of 28 years shares facilities with a score of researchers, all of whom are South Koreans, and is dedicated to insert genetic codes in complex sequences of DNA that are subsequently introduced into the cells to clone. Source of the news: dogs cloned and engineered to glow in the dark: research or business?